Diffusion tensor tractography of normal and compressed spinal cord:a preliminary study at 3.0 T MR
- VernacularTitle:3.0 T MR扩散张量纤维束示踪在显示正常脊髓及诊断脊髓压迫症中的作用
- Author:
Wei WANG
;
Shi-Xin CHANG
;
Jian-Ping LU
;
Nan-Xin HAO
;
Cheng ZHAO
;
Wen QIN
;
Yu-Shan DU
;
Yi-Bin WANG
;
Gen-Lin ZONG
;
Kai-Ming CAO
- Publication Type:Journal Article
- Keywords:
Magnetic resonance imaging;
Spinal cord compression;
Diffusion
- From:
Chinese Journal of Radiology
2001;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the feasibility and clinical values of diffusion tensor tractography (DTT)in the spinal cord at 3.0 T MR.Methods Forty patients with spinal cord compression including cervical cord herniation and cervical spondylosis(30 cases),tumors in spinal canal(9 cases)and old injury in cervical vertebrae(1 cases)and 20 healthy volunteers participated in this study.Single-shot spin- echo echo-planar diffusion tensor sequence for tractography of the spinal cord was performed.The fibers of spinal cord were visualized by using fiber tracking software.Results On the DTT maps,the normal spinal cord was depicted as a fiber tract showing color-encoded cephaloeaudally,which indicated anisotropy in the cephalocaudal direction.By setting two ROI,the main spinal cord fiber tracts,such as corticospinal or spinothalamic tract,were visualized.The tracts from two sides of the brain did not completely cross.It was asymmetric in the number of tracts on the two sides in most normal subjects(8/10).The tracts of all patients with cord compression were seen oppressed or damaged in different degrees.The DrrT in patients with cervical spondylosis and extramedullary-intradural neurolemmoma demonstrated that tracts were oppressed but not damaged.The DTT in one ependymoma showed that tract was markedly compressed and slightly damaged.Conclusion DTT is a promising tool for demonstrating the spinal cord tracts and abnormalities,can provide useful information for the localization of compression and evaluation of the impairment extent on the white matter tracts of the spinal cord.
