Evaluation of the correlation between cerebral blood volume and permeability surface from CT perfusion images with glioma grade
- VernacularTitle:胶质瘤CT灌注成像对脑血容量与血管表面通透性的相关性研究
- Author:
Bei DING
;
Hua-Wei LING
;
Huan ZHANG
;
Qi SONG
;
Hai-Peng DONG
;
Ke-Min CHEN
;
- Publication Type:Journal Article
- Keywords:
Tomography,X-ray Computed;
Glioma;
Perfusion
- From:
Chinese Journal of Radiology
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the correlation between cerebral blood volume and permeability surface by using muhislice CT perfusion imaging with glioma grade.Methods Ninteen patients with gliomas underwent conventional MR and multislice CT perfusion imaging preoperatively.These patients were divided into low grade and high grade groups which were correspond to WHO Ⅱ grade gliomas and WHO Ⅲ or Ⅳ grade gliomas respectively.CT data were transferred to on-line working station and processed to obtain time-signal curves,color perfusion maps and calculated perfusion parameters,including cerebral blood volume(CBV),cerebral blood flow(CBF),mean transit time(MTT)and permeability surfaces (PS)in tumoral parenchyma.Kruskal-Wallis test and correlation of CBV and PS was assessed by using SPSS 11.0 software.Results The median of CBV and PS in low-grade and high-grade glioma were 2.7, 6.5 ml/100 g;0.389,12.810 ml?100 g~(-1)?min~(-1),respectively,corresponding t value were 12.907, 13.500 with P
