Dynamic image-pathological investigation on MR diffusion weighted imaging in rabbit liver VX_2 tumor model
- VernacularTitle:兔肝VX_2瘤MR扩散加权成像与病理的动态对照研究
- Author:
You-Hong YUAN
;
En-Hua XIAO
;
Jian-Bin LIU
;
Zhong HE
;
Ke JIN
;
Cong MA
;
Jun XIANG
;
Jie-Hua XIAO
;
Wei-Jian CHEN
;
Zi-Wen PENG
- Publication Type:Journal Article
- Keywords:
Carcinoma,hepatocellular;
Magnetic resonance imaging;
Rabbits;
Comparative study
- From:
Chinese Journal of Radiology
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value and dynamic characteristics of diffusion-weighted imaging(DWI)in rabbit liver VX_2 tumor model,with correlation of pathology.Methods Forty New Zealand rabbits were included in the study and VX_2 tumor piece was implanted directly into the liver after laporotomy.Fiffteen had two intrahepatic implants while twenty-five had one implant.DWI was performed on the seventh,fourteenth and twenty-first day after implantation,while routine T_1WI and T_2WI sequences were done on the seventh and fourteenth day.Ten VX_2 tumor samples were studied by pathology.Results The lump detection rates on the seventh day after implantation of DWI,T_1WI and T_2WI were 78.7%(37/47), 10.7%(3/28)and 53.6%(15/28)respectively with statistical significance(x~2=32.61,P
