Study on the role of serum cytokine in the patients of HBV recurrence after liver transplantation.
- VernacularTitle:细胞因子在肝移植术后HBV复发中的作用
- Author:
Hongli SONG
;
Zhongyang SHEN
;
Daihong LI
;
Al ET
;
- Publication Type:Journal Article
- Keywords:
IL-10;
TNF-?;
IL-2;
INF-?;
liver transplantation;
HBV recurrence
- From:
Chinese Journal of Practical Internal Medicine
2006;0(S2):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the role of cytokine levels for prediction of HBV recurrence after liver transplanta- tion.Methods 34 cases of liver transplantation from June 2002 to December 2003 in our hospital were observed.The measurements of cytokine in serum by ELISA method were taken on the 7 days before operation and recurrence after oper- ation and the change rules were studied.Results The serum TNF-?,IL-10和 INF-? levels gradually increased in HBV non-recurrence group,but which in recurrence group had no markedly change and always skept on normal levels after operation.In addition,the serum TNF-?和 IL-10 levels after operation were significantly higher in nonrecur- rence group than in recurrence group.The serum IL-2 levels in recurrence group always kept on higher levels without marked changes after operation.Conclusion TNF-? and IL-10 are better laboratory index in the prediction of HBV recurrence after liver transplantation and which are noninvaded and cheap.
