Expression of CA199,CA724 and CEA in gastric cancer and clinical significance.
- VernacularTitle:CA199 CA724 CEA在胃癌中的表达及临床意义
- Author:
Xueping ZENG
;
Wei QU
;
- Publication Type:Journal Article
- Keywords:
Gastric cancer;
CA199;
CA724;
CEA;
Immunohistochemistry
- From:
Chinese Journal of Practical Internal Medicine
2006;0(S2):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the express levels of CA199,CA724 and CEA in different gastric mucosa pathological situation.Methods The experimental group included 82 cases including 15 of chronic atrophic gastritis,15 of intesti- nal metapiasia,15 of dysplasia of the gastric mucosa,19 of gastric ulcer,18 of gastric cancer;15 of the chronic Super- ficial gastritis (CSG) were set as control group.To test express levels of CA199,CA724 and CEA in these cases by the immunohistochemistry technology.Results The positive rate of CA199,CA724 and CEA in gastric cancer was sig- nificantly higher than that in precancerous lesion groups and precancerous state groups (P0.05),but there was a graduate increasing of the positive rate of CA199,CA724 expression in chronic atrophic gastritis,intestinal metaplasia and dysplasia of the gastric mucosa. Conclusion That different expression of CA199,CA724 and CEA in gastric cancer development situation may be help- ful for the early diagnose of gastric cancer.
