Therapeutic effect observation of combined defibrase with mannitol in treating acute cerebral infarction.
- VernacularTitle:降纤酶与甘露醇联合治疗急性脑梗死的疗效观察
- Author:
Xiaofei WANG
;
Sengquan LU
;
Qiang WANG
;
- Publication Type:Journal Article
- Keywords:
Cerebral infarction;
Defibrase;
Mannitol
- From:
Chinese Journal of Practical Internal Medicine
2006;0(S2):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyse the clinical efficacy of combined defibrase with mannitol in treating acute cerebral in- farction.Methods 64 cases with acute cerebral infarction were randomly divided into treated group (34 cases) and control group (30 cases),The patients in treated group were treated intravenously with defibrase 10 U per diem and 20% mannitol 250 mL twice a day,The 30 patients in control group treated with defibrase alone.The treatment course of both groups was 14 days,the nerve function deficit score was evaluated before and the 15th day,the routine life abili- ty (Barthel Index) was evaluated,Therapeutic efl'ects and adverse effects were observed.Results After treatment, The nerve function deficit score and The Barthel Index improved much more than those of the control group (P
