Anticancer effect of tea polyphenols on implanted breast cancer
- VernacularTitle:茶多酚抗移植性乳腺癌作用的研究
- Author:
Yan-Ming ZHANG
;
Li XU
;
Xin-Yi CHEN
;
Neoplastic HEMATOLOGY
;
- Publication Type:Journal Article
- Keywords:
Tea polyphenols;
Breast cancer (EMT6);
Antitumor effect
- From:
International Journal of Traditional Chinese Medicine
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the growth inhibiting effect of tea polyphenols on implanted mouse breast cancer(EMT_6),and offer the foundation for the next study on its inhibiting angiogenesis effect and its molecular mechanism.Methods Mammary adenocarcinoma EMT_6 was cultured and propagated,then implanted on female BALB/c mice.Tea polyphenols was peroral administrated and local injected.Anticancer function was determined with regular methods.Result After tea polyphenols were taken by oral and local injection on EMT_6 mammary adenocarcinoma mice,the inhibitory ratio of tumor are respectively 37.43% and 40.94%.Conclusion Tea polyphenols had significant inhibitive effect on implanted breast cancer.This offered the foundation for the next intensiVe study on its inhibiting angiogenesis effect and its molecular mechanism.
