Effects of Small Qinglong Decoction Medicine-Containing Serum on ASMC Proliferation Action Induced by ET-1
- VernacularTitle:小青龙汤含药血清对内皮素-1诱导的气道平滑肌细胞增殖作用的影响
- Author:
Hanrong XUE
;
Guangxiang HONG
;
Guangyu CHENG
;
Xiangchun FU
;
Zhihui LAN
;
Lihua WANG
;
Seqi LIN
;
- Publication Type:Journal Article
- Keywords:
Small Qinglong Decoction;
medicine-containing serum;
airway smooth muscle cell(ASMC);
proliferation
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the effects of Small Qinglong Decoction medicine-containing serum on ASMC proliferation action induced by ET-1.Methods: There were six groups in the experiment: normal group(10% normal control serum),model group(ET-1 added 10% normal control serum),Small Qinglong Decoction high dose group(ET-1 added 10% Small Qinglong Decoction high dose serum),Small Qinglong Decoction middle dose group(ET-1 added 10% Small Qinglong Decoction middle dose serum),Small Qinglong Decoction low dose group(ET-1 added 10% Small Qinglong Decoction low dose serum) and Dexamethasone group(ET-1 added 10% Dexamethasone serum),eight slots every group.ASMC proliferation status of 24h,48h and 72h were detected with MTT chromometry.Results: Compared with model group,ASMC proliferation in Small Qinglong Decoction low dose group medicine-containing serum each stage and middle dose group24h and 72h all had significant difference(P
