The comparative study of adrenal medulla hyperplasia in rats on MRI and pathological examination
- VernacularTitle:大鼠肾上腺髓质增生MRI与病理的对比研究
- Author:
Yong-Mei YU
;
Jian ZHAI
;
Guo-Jie LI
;
Yuan-Jun CHEN
;
Zheng-Rong ZHANG
;
- Publication Type:Journal Article
- Keywords:
Adrenalmedulla;
Hyperplasia;
Magneticresonanceimaging;
Rats
- From:
Chinese Journal of Radiology
1999;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the value of Magnetic resonance imaging(MRI)technique on diagnosis of adrenal medulla hyperplasia model rats confirmed by pathology study.Methods Sixty male SD rats were divided into 6 groups randomly,10 rats in each group.As experiment group,A,B,C groups were subcutaneously injected with reserpine(0.4 mg?kg~(-1)?d~(-1))from the beginning to 40,60,80 days respectively.As compare,the control groups(a,b,c group)were only injected with sodium chloride simultaneously.MRI technique and pathology study were performed for all the subjects on 40,60,and 80 days respectively.Results The percent of medulla were higher in B and C groups than that in b and c groups respectively[(34.3?5.8)% vs.(25.7?8.9)%,t=2.462,P
