Correlative study between MRI signal intensity of the lumbar intervertebral disc and collagen content in the nucleus pulposus
- VernacularTitle:腰椎间盘MRI信号强度与髓核胶原蛋白含量的相关性
- Author:
Wen-Chang YU
;
Jian-Yong YANG
;
Wen-Quan ZHUANG
;
Yun-Bin CHEN
;
Shi-Fang ZHENG
;
- Publication Type:Journal Article
- Keywords:
Lumbarvertebrae;
Intervertebraldiscdisplacement;
Magneticresonanceimaging;
Collagen
- From:
Chinese Journal of Radiology
1999;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study correlation between MRI signal intensity of the lumbar intervertebral disc and collagen content in the nucleus pulposus.Methods Thirty-one cases with lumbar intervertebral disc herniation(male 21,female 10)received percutaneous lumbar disketetomy.Thirty-one specimens of nucleous pulposus were obtained from percutaneous lumbar disketctomy procedure and collagen content in them was measured with reformed hydroxyproline measurement method.The signal intensity(SI) of lumbar intervertebral disc and cerebrospinal fluid was measured in T_2 WI sagittal image and then ratio of disc SI to cerebrospinal fluid SI was calculated.The Pearson analysis was used to analyze the correlation between the collagen content and SI ratio and disc SI on T_2 WI.Results Collagen content and SI ratio were (231.0?63.5)mg/g and 0.19?0.07,respectively.There was negative correlation between them (r=-0.61,P
