Effects of cilazapril on endothelial and flbrinolytic function in atrial fibrillation.
- VernacularTitle:西拉普利对心房颤动患者内皮和纤溶功能的影响
- Author:
Xiaoli LIU
;
Xiaomei WANG
;
- Publication Type:Journal Article
- Keywords:
Atrial fibrillatim;
Endotheial;
Fibrinolyfic funefim;
Cilazapril
- From:
Chinese Journal of Practical Internal Medicine
2006;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe endothelial and fibrinolytic functions of clinical AF patients and effects of cilazapril on it and to investigate the mechanism and treatments of thrombogenesis in AF.Methods 63 AF patients were randomly divided into control group(n=30)and cilazapril group(n=33).All patients received general treatment according symptoms.In addition,the patients in cilazapril group received cilazapril(2.5mg/d,2 weeks).Plasma Ang Ⅱ, vWF,t-PA and PAI-1 level were measured before and after 2 weeks.There were 36 patients with sinus rhythm (SH)in non-AF control group.Results AF patients had higher plasma Angll level than SH patients that indicated RAS activated[(107.7?22.0)pg/mL vs(70.2?15.8)pg/mL,P
