The expression ofp21~(WAF1)gene and p53 protein in tuberculosis with lung cancer.
- VernacularTitle:p21~(WAF1)基因及p53蛋白在肺结核合并肺癌组织中的表达
- Author:
Xiaomei FU
;
Anjia HAN
;
Shuling ZHU
;
Al ET
;
- Publication Type:Journal Article
- Keywords:
Lung carcinoma;
p21~(WAFt)gent;
p53 protein;
Munohistochemistry
- From:
Chinese Journal of Practical Internal Medicine
2006;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the role of cell cycle regulator in tuberculosis with lung cancer.Methods The ex- pression of p21~(WAF1)gene and p53 protein in 101 cases of tuberculosis with lung cancer have been detected by immunohis- toehemical method.Results total positive staining rate of p21~(WAF1)gene and p53 protein was 42.9% and 64.1%; The expression of both was correlated with histological classification and differentiation of carcinoma.Conclusion Detection of p21W AF1 gene and p53 protein expression may have significant value in the prognosis of tuberculosis with lung cancer
