Influence and significance of atorvastatin on serum C-reactive protein level in acute cerebral infarction pa- tients.
- VernacularTitle:阿托伐他汀对急性脑梗死患者血清C反应蛋白水平的影响及意义
- Author:
Yuming WAN
;
Xiuhong WANG
;
Junhua HUANG
;
- Publication Type:Journal Article
- Keywords:
Atorvastatin;
C-reactive protein;
Acute cerebral infarction
- From:
Chinese Journal of Practical Internal Medicine
2006;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective It is to study the influence of atorvatatin on serum C-reactive protein(CRP)level in acute cer- ebral infarction patients and to analyze its clinical significance.Methods 62 patients with acute cerebral infarction di- agnosed by CT or MRI were chosen and divided into two groups randomly.Both the groups were treated with normal method and the treatment group was given atorvastatin 20mg per day.Serum CRP levels in the two groups were measured by immunnturbidimetry within24h after final diagnosis and at two weeks the level decreased obviously in treatment.Re- slllts Serum CRP levels all increased in the patients.After treatment for two weeks the level decreased obviously in treatment group.The difference was significant compared with control group.Conclusion Atorvastatin can markedly reduce the serum CRP level in acute cerebral infarction patients and has important significance for the pathogenetic condi- tion change and prognosis of cerebral infarction.
