Effects of Tea Polyphenols on Tumor-inhibiting Rate in Transplantation S_(180) Mice Tumor Models
- VernacularTitle:茶多酚对移植性S_(180)小鼠肿瘤模型抑瘤率的影响
- Author:
Li XU
;
Li HOU
;
Jie LIU
;
Al ET
;
- Publication Type:Journal Article
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To establish transplantation S_(180)mice of tumor animal models in order to observe the tumor-inhibiting rate of tea polyphenols given by oral administration,intravenous injection and local injection.Method: In order to observe the different tumor-inhibiting effects,transplantation S_(180)mice tumor models were randomly given tea polyphenols orally with large,medium and small dosages,locally with large,medium and small dosages,and intraperitoneally with large,medium and small dosages.And different control groups were set up in terms of panaxsaponin Rg3 control group,cyclophosphamide control group and model control group.Result: The tumor inhibiting rates of tea polyphenols in different dosages and different routes of administration were all above 30%.Different dosages and different ways of giving tea polyphenols showed statistical significance as compared with the model control group(P
