Effects of Compound Konjac Glucomannan on Hyperlipidemia in Rats
- VernacularTitle:复方魔芋葡甘聚糖对大鼠高脂血症的影响
- Author:
Jiaqing HE
;
Xunduan HUANG
;
- Publication Type:Journal Article
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: The experiment was designed to study the effects of compound Konjac glucomannan on hyperlipidemia for the purpose of improving the therapeutic efficacy. Method: First, hyperlipidemia rat models were established. Then the effects of compound Konjac glucomannan and Konjac glucomannan on blood lipids levels and hepatic tissue morphous of rats were detected. Result; The compound Konjac glucomannan could decrease LDL-C and ApoB levels of serum TC significantly, while notably increase HDL-C and ApoA-1 levels. The result also shows that compound Konjac glucomannan could obviously improve the TG metabolism and decrease blood glucose concentration. The morphologic observation indicates that both Konjac glucomannan and flavonids could protect liver tissues of rats. Conclusion; Compound Konjac glucomannan could improve regulative ability of lipids metabolism and decrease serum lipids levels.
