Effects of the Volatile Oil of Sandwort on Expression of CD54 in the Bronchial Epithelium Tissue of Acute Lung Injury Rat
- VernacularTitle:鹅不食草挥发油对急性肺损伤大鼠支气管上皮细胞CD54表达的影响
- Author:
Ren'An TAN
;
Jingli SHI
;
WANLEI
;
Al ET
;
- Publication Type:Journal Article
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the anti-inflamation effect of Volatile oil of Centipesa minima and the mechanism of action. Method: The “Two-hit” animal model of acute lung injury in rats was induced by oleic acid and lipopolysaccharide, to observe the protective effect of VOCM on acute lung injury in rats. Result: VOCM was able to suppress lung edema and high numbers of neutrophils, decrease the expression of CD54 in the bronchial epithelium tissue in the acute lung injury animal models. Conclusion: VOCM has a protective effect on acute lung injury in rats. Decreasing the expression of CD54 in the bronchial epithelium tissue may be one of its mechanisms of against respiratory tract inflammation.
