Effect of Longqincao Spray (LQC) on Relieving Fever and Changing TNF-? Lever
- VernacularTitle:龙芩草喷雾剂的解热作用及对肿瘤坏死因子的影响
- Author:
Xuhua HAN
;
Yanyan NIUXIN
;
Al ET
;
- Publication Type:Journal Article
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the effect of LQC on relieving fever in rabbits and the effect on secretion of TNF-?, probe into the correlated mechanism of LQC on pharmacological action and its substance basic of “treating different diseases with the same therapeutic principle”. Method: Rabbit pyrexia model was made by injecting lipopolysacchatide (LPS) into auris edge vein, and alveolar epithelial cell II damnification model was made by adding LPS to culture medium. The change of temperature and TNF-?lever in cell culture supernate were observed before or after using LQC. Result: LQC can resist the temperature rising by LPS, relieve pyrexia reaction, restrain the augment of TNF-?content. Conclusion: The results suggested that LQC possess distinct function of relieving fever, which is likely related to restraining the abnomal augment of TNF-?.
