Multi-slices spiral CT perfusion imaging evaluating of microvessel density in maxillofacial tumors
- VernacularTitle:多层螺旋CT灌注成像评价颌面部肿瘤微血管密度的研究
- Author:
Chuan-Ting LI
;
Yu-Bo LV
;
Dong-Sheng ZHANG
;
Wei-Dong ZHANG
;
Jing-Guang LV
;
Cheng LIU
;
Le-Bin WU
;
- Publication Type:Journal Article
- Keywords:
Head and neck neoplasms;
Microvessel density;
Tomography,X-ray computed;
Perfusion imaging
- From:
Chinese Journal of Radiology
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the relationship between Multi-slices spiral(MSCT) perfusion and microvessel density (MVD) in maxillofacial tumors. Methods Thirty-one cases of maxillofacial tumors were studied with MSCT perfusion imaging before operation. The time-density curve, perfusion, time to peak(TTP), and Peak enhancement imaging (PEI) of tumors were calculated. MVD of the tumors was measured with immuno-histochemical method by means of detecting factor Ⅷ in all the histologic specimens. Relativity analysis was carried between MSCT perfusion imaging parameters, perfusion curve types and MVD. Results MVD of maxillofacial tumors were higher than normal tissue. MVD remarkably correlated with malignancy of the tumors. Perfusion and time to peak (TTP) correlated well with MVD(t=7.09,4.10, P0.05). Significant difference of MVD in three types of perfusion curve was found(F=8.09,P
