Interactions between angiotensin converting enzyme inhibitors and aspirin
- VernacularTitle:血管紧张素转化酶抑制药和阿司匹林联合用药的相互作用
- Author:
Xiong-Wen LV
;
Jun LI
;
- Publication Type:Journal Article
- Keywords:
angiotensin converting enzyme inhibitors;
aspirin;
drug int eraction
- From:
Chinese Pharmacological Bulletin
1987;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Both aspirin and angiotensin converting enzyme(ACE)inhi bi tors are often used concomitantly in patients with cardiovascular disease.The s afety of the combination has been questioned. The potential antagonistic interac tions between ACE inhibitors and aspirin has become the focus of both increasing research and intense debate,with conflicting conclusions havin g been reported in the literature.We reviewed systematically available literatu re on the interactions between ACE inhibitors and aspirin in hyper- tension,acute myocardial infarction and congestive heart failure and found that further trials are needed to shed light on the effects and mechanism of interaction between these drugs.