Study on the changes of indirect biliburin in obstructive sleep apnea hypopnea syndrome before and after continuous positive airway pressure ventilation

VernacularTitle:阻塞性睡眠呼吸暂停低通气综合征持续正压通气呼吸机治疗前后间接胆红素水平变化的研究
Author: Hong SU ; Xueyuan CHEN ; Jianquan ZHANG ; Al ET ;
Publication Type:Journal Article
Keywords: Obstructive sleep apnea hypopnea syndrome; Heme oxygenase; Indirect bilirubin
From: Chinese Journal of Respiratory and Critical Care Medicine 2003;0(06):-
CountryChina
Language:Chinese
Abstract: Objective To investigate the changes of plasma indirect bilirubin(IDB) and its role in the pathogenesis of obstructive sleep apnea hyponea syndrome(OSAHS).Methods Plasma IDB levels were detected in 30 healthy controls and 20 patiemts with OSAHS by improved J G method with 7170A automatic biochemistry analytical apparatus.Plasma IDB levels in OSAHS were compared before and an overnight or a month after CPAP treatment.ResultsPlasma IDB levels in controls were significantly higher than those in OSAHS [(16 2?5 0) ?mol/L vs (8 0?3 5)?mol/L, P 0 05] and markedly increase after a month CPAP ventilation [(8 0?3 5) ?mol/L vs (14 0?5 0)?mol/L, P