Radiotherapy combined with arterial infusion chemotherapy for locally advanced and recurrent rectal cancer
- VernacularTitle:局部晚期和复发直肠癌放射治疗配合动脉灌注化疗疗效分析
- Author:
Xiuying LIU
;
Huiling LI
;
Jiancheng LI
;
Lifeng WANG
;
Furong GUO
;
Jianji PAN
;
- Publication Type:Journal Article
- Keywords:
Rectal neoplasms/radiotherapy;
Rectal neoplasms /chemotherapy;
Arterial infusion
- From:
Chinese Journal of Radiation Oncology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of radiotherapy(RT)combined with arterial infusion chemotherapy(AIC) in the treatment of locally advanced or recurrent rectal cancer. Methods From May.1994 to Dec.2000, 62 patients with locally advanced or recurrent rectal cancer were randomized into two groups: RT alone group(31 patients)and the combined group(RT+AIC, 31 patients). All patients were treated with conventional radiotherapy by 8 18 ?MV X ray to a total dose of D T40 50 ?Gy in 4 to 5 weeks for the resectable disease, or to a dose of 60 70 ?Gy in 6 to 7 weeks for the unresectable disease. However, the combined group received concurrent arterial infusion chemotherapy by DDP 70?mg/m 2 and 5 FU 600 ?mg/m 2 in 2 3 cycles. Results The response rates were 83.9% and 54.8% in combined group and RT alone group, respectively (P
