Study of the correlation of cerebral CT and P300 in 30 patients with Alzheimer's disease
- VernacularTitle:30例老年性痴呆患者脑CT与P300的相关性研究
- Author:
Lili ZHANG
;
Jingzhou WANG
;
- Publication Type:Journal Article
- Keywords:
Alzheimer's disease;
cerebral CT;
P300
- From:Journal of Third Military Medical University
2003;0(17):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the changes of cerebral CT and auditory event related potentials (ERP, P300) for finding the effective method for the comprehensive evaluation of the patients with Alzheimer's disease. Methods Cerebral CT, P300, and Mini Mental State Examination (MMSE) were employed to assess 30 patients with Alzheimer's disease. Results Latency and amplitude of wave of P300 in patients were prolonged and decreased, respectively. Cerebral CT found an obvious atrophy in the frontal and temporal lobes of cerebra. These changes were obviously correlated with the severity of dementia. Conclusion Using cerebral CT, P300, and MMSE can offer morphometric, functional and psychological information which is helpful for precise assessment of patients with Alzheimer's disease.
