Clinical observation on prevention of diabetes complicated with pulmonary tuberculosis by Mycobacterium vaccae vaccine
- VernacularTitle:采用母牛分支杆菌菌苗预防糖尿病患者并发肺结核的临床观察
- Author:
Zhongmin HUANG
;
Qiwen HUANG
;
Yaqin QIN
;
- Publication Type:Journal Article
- Keywords:
Mycobacterium vaccae;
vaccine;
tuberculosis;
diabetes
- From:Journal of Third Military Medical University
2003;0(16):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect and safety of Mycobacterium vaccae vaccine ( M. vaccae vaccine) on diabetes patients complicated with pulmonary tuberculosis. Methods A total of 76 diabetes patients complicated with pulmonary tuberculosis were randomized into immunotherapy group (M, n =38) and control group (C, n =38). Administration of routine anti diabetic drugs and diet treatment were conducted in both groups. In addition, patients in group M were treat with additional M. vaccae vaccine for 3 months, but those in group C were not. Results At the end of the treatment, no side effects of M. vaccae vaccine were found in group M, but immunological function of T cells was significantly improved. Compared with those in group C, CD3 and CD4 in group M were significantly higher ( P
