The role of calcitonin gene-related peptide in hypertension
- VernacularTitle:降钙素基因相关肽与高血压
- Author:
Panyue DENG
;
Yuanjian LI
;
- Publication Type:Journal Article
- Keywords:
calcitonin gene-related peptide (CGRP);
hypertension;
sensory nerves;
capsaicin
- From:
Chinese Pharmacological Bulletin
2003;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
The sensory merves innervate blood vessels all over the body and participate in the regulation of cardiovascular function both in the normal state and in the pathophysiology of hypertension through the actions of potent vasodilator neuropeptides Calcitonin gene related peptide, the predominant neurotransmitter in the capsaicin sensitive sensory nerves, plays an important role in the initiation and progression of hypertension via the alterations in its synthesis and release.