Experimental study on progestogen activity of triphasic contraceptive tablets
- VernacularTitle:三相避孕片的孕激素活性研究
- Author:
Zhaoyang HU
;
Fangju YANG
;
Min ZHANG
;
Ling ZHU
;
Bangliang XIAO
;
Suzhen ZHOU
;
- Publication Type:Journal Article
- Keywords:
triphasic contraceptive tablets;
uterus weight increase;
endometrium translation;
progestogen activity;
radialized receptor analysis
- From:
Chinese Pharmacological Bulletin
2003;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Aim To study the progestogen effect and activity of triphasic contraceptive tablets.Methods The progestogen activity of triphasic contraceptive tablets (kalirui and trinordiol) was evaluated through uterus weight increase test of female young mice and endometrium translation examination of female young rabbits. Radialized receptor analysis was used to determine the effect of the triphasic contraceptive tablets on progestogen receptor by the uterus histiocyte from the adult female rabbits whose ovaries had been taken away a week ago. Results Compared with the negative control, triphasic contraceptive tablets kalirui andtrinordiol in three phase groups not only enhanced uterus weight of female young mice, middle and high dose groups obviously accelerated the uterus weight increase ( P
