Serum level of Interlukin 18 and nitric oxide and the effect of N-acetylcysteine in patients with fulminant hepatic failure
- VernacularTitle:慢性重型肝炎患者早期血清IL-18和NO水平变化及N-乙酰半胱氨酸对其的影响
- Author:
Hongying PAN
;
Guoqiang LOU
;
Nianfeng ZHAO
;
Al ET
;
- Publication Type:Journal Article
- Keywords:
Hepatitis, viral, human;
Interleukin 18;
nitric oxide;
acetylcysteine
- From:
Chinese Journal of Infectious Diseases
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate whether there is a correlation of serum interleukin 18 (IL 18) and nitric oxide (NO) with Fulminant Hepatic Failure(FHF) and the effect of N acetylcysteine (NAC) on IL 18 and NO levels. Methods The level expression and dynamic changes of serum IL 18 and NO in 65 FHF patients serum were measured by ELISA. IL 18 and NO and their expression levels were observed comparatively in NAC treatment group (29 cases) and composite treatment group (36 cases). Results Serum IL 18 and NO concentrations in patients with FHF in both groups (NAC and Combination) were significantly higher than the control ( P
