Relationship between matrix metalloproteinase-9 activity and microemboli formation in patients with cerebral infarction and its clinical significance
- VernacularTitle:脑梗死患者血浆基质金属蛋白酶-9与微栓子形成的关系及临床意义
- Author:
Jiying ZHOU
;
Guoguang PENG
;
Wenwei XIE
;
Weiwei DONG
;
- Publication Type:Journal Article
- Keywords:
cerebral infarction;
transcranial Doppler;
embolism;
matrix metalloproteinase-9
- From:Journal of Third Military Medical University
2003;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relation between plasma matrix metalloproteinase 9 (MMP 9) levels and transcranial Doppler (TCD) detected microemboli in patients with cerebral infarction and evaluate the clinical significance. Methods The plasma MMP 9 levels were quantified by ELISA and the microemboli were detected with TCD in 50 stroke patients and 20 controls. Results The level of plasma MMP 9 was significantly higher in microembolic signal positive patients than that in negative ones [median (392.87?210.90) ng/ml for those with emboli versus (202.27?153.40) ng/ml for those without, P
