Nuclear factor-?B and the pathegenesis of the atherosclerosis
- VernacularTitle:NF-?B在动脉粥样硬化中的始动作用
- Author:
Cuige SHI
;
Gang HU
;
Hai WANG
;
- Publication Type:Journal Article
- Keywords:
atherosclerosis;
endothelial cells;
NF ?B
- From:
Chinese Pharmacological Bulletin
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Atherosclerosis is a pathegenesis process involved in the inflammatory and proliferative responses of cells in which endothelial cells have an important function in the regulation of a variety of genes. A variety of molecules have been identified in the atherosclerotic environment that are able to activate NF ?B. Possible functional implications for activated NF ?B in atherogenesis are discussed by protecting endothelial cells selectively, perhaps, it may provide a new method for the therapy of the atherosclerosis.
