Related factors and mechanism of impaired glucose tolerance in human with sepsis
- VernacularTitle:脓毒症病人糖耐量异常的相关因素及机制研究
- Author:
Wenkui YU
;
Weiqin LI
;
Ning LI
;
Jieshou LI
;
- Publication Type:Journal Article
- Keywords:
Sepsis;
IGT;
Hormone;
Cytokine
- From:
Parenteral & Enteral Nutrition
1997;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objectives: To study the related factors and mechanism of the impaired glucose tolerance(IGT) in human with sepsis. Methods: According to the results of intravenous glucose tolerance test, forty patients were classified into two groups: 16 control subjects and 24 IGT subjects. The counterregulatory hormone, the basal levels of plasma insulin, glucagons, cortisol, IL 6 and TNF ? were compared in two groups, and the change of inflammatory cytokine and counterregulatory hormone after dextrose infusion were observed. Results: The severity of the disease (APACHEⅡscore, Sepsis score), mixed infection and bacteremia were significantly related to the results of glucose tolerance test( P
