Changes of BMD and the causing factors in menopausal female patients with type Ⅱ diabetes mellitus
- VernacularTitle:绝经后女性2型糖尿病患者骨密度改变及影响因素的初探
- Author:
Zhengping FENG
;
Delan YANG
;
Ping MENG
;
Bing CHEN
;
- Publication Type:Journal Article
- Keywords:
typeⅡdiabetes;
osteoporosis;
urine albumin excretion rate;
glycated hemoglobin
- From:Journal of Third Military Medical University
2003;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the changes of bone mineral density (BMD) and its causing factors in menopausal female patients with type Ⅱ diabetes mellitus (DM2). Methods Dual energy X ray absorptimetry was used to measure the BMD of lumbar spines (L 2-4 ) and proximal femur in 82 female patients with type Ⅱ diabetes and 46 normal controls. According to BMD, DM2 patients were divided into two groups (DM A and DM B). Fasting plasma glucose (FPG), fasting plasma insulin (FINS), fasting plasma C peptide (FCP), glycated hemoglobin (HbAc1), urine albumin excretion rate (UAER), and urine ? 2 microglobin (? 2 MG) were measured and compared between the two groups. Results BMD of lumbar spines (L 2-4 ), femoral neck and Ward's triangle in diabetic patients were significantly lower than that of the controls ( P