Change of serum interleukin-6 levels in obese patients and effect of sibutramine on its levels
- VernacularTitle:单纯性肥胖患者血清IL-6水平的变化及西布曲明减重治疗对其的影响
- Author:
Congrong GAO
;
Linghui YANG
;
Qijin WANG
;
Dajin ZOU
;
- Publication Type:Journal Article
- Keywords:
obesity;
interleukin 6;
sibutramine
- From:
Academic Journal of Second Military Medical University
1981;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the change of serum interleukin 6 levels in obese patients and effect of sibutramine on its levels.Methods:Totally 45 obese patients were assigned into sibutramine treated group( n =25) and placebo treated group( n =20), and 16 normal weight subjects were taken as control group.Before and after 24 week treatment,body mass,waist circumferences,serum levels of interleukin 6,glucose and insulin were determined,and the body mass index(BMI) and HOMA IR were calculated.Results:(1) Body mass,BMI and waist circumferences decreased after 24 week treatment in sibutramine and placebo group( P
