Self-emulsifying preparation of evening primrose oil
- VernacularTitle:月见草油自乳化制剂处方研究
- Author:
Guodong LI
;
Wei FAN
;
Guohao LU
;
Shen GAO
;
Yong ZHANG
;
- Publication Type:Journal Article
- Keywords:
evening primrose oil;
self emulsifying;
dosage form improving
- From:
Academic Journal of Second Military Medical University
1981;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To search for the optimum formula for the self emulsification of evening primrose oil. Methods: Through solubility experiment, orthogonal screen and drawing phase diagram, taking the degree of emulsifying, the volume of the rest oil and emulsion particle size as parameters,the oil, non ionic surfactant and flux for the optimum formulation were screened. Results: In the formulation of evening primrose oil, taking Tween 85 as the non ionic surfactant and propylene glycol as the co surfactant can get the best effect of emulsifying. Conclusion: The optimum formula for self emulsification of evening primrose oil is evening primrose oil, Tween 85 and propylene glycol,with their proportion being 5∶7∶3.
