Radioimmunoassay of TNF?, IGF, and TGF? in proliferative vitreoretinopathy
- VernacularTitle:TNF-?、IGF、TGF-?在增殖性玻璃体视网膜疾病中的表达
- Author:
Fang GAO
;
Yi WANG
;
Shaojun CHEN
;
Yong LIU
;
- Publication Type:Journal Article
- Keywords:
vitreoretinopathy;
radioimmunoassay;
tumor necrosis factor ?;
insulin like growth factor;
transforming growth factor ?
- From:Journal of Third Military Medical University
1988;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To measure the levels of tumor necrosis factor ? (TNF?), insulin like growth factor (IGF), and transforming growth factor ? (TGF?) in the pathogenesis of proliferative vitreoretinopathy (PVR), traumatic proliferative vitreoretinopathy (TPVR), and proliferative diabetic retinopathy (PDR). Methods The levels of TNF?, TGF?, and IGF in vitreous samples taken from 56 patients and 13 normal subjects were determined by radioimmunoassay (RIA). Results The levels of TNF? and IGF in vitreous samples from patients with PVR, TPVR, and PDR increased significantly, as compared with those of the normal controls ( P 0.05). Conclusion TNF? and IGF participate in the pathogenesis of PVR, TPVR, and PDR.
