Expression of protooncogene C-mer in hypertrophic scar and its significance
- VernacularTitle:C-mer在增生性瘢痕中表达与意义
- Author:
Zhenxiang WANG
;
Shirong LI
;
Jun WU
;
- Publication Type:Journal Article
- Keywords:
hypertrophic scar;
cytoskeleton gene;
protooncogene;
C mer
- From:Journal of Third Military Medical University
1983;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the roles of protooncogene C mer in hypertrophic scar and its significance. Methods Specimens were collected from patients. Oligonucleotide probe made using the specific fragment of protooncogene C mer was hybridized with the frozen slices of scar tissues and cultured fibroblasts. Changes of gene expression were detected by in situ hybridization. Results Stronger C mer expression was found in scar tissue than that in normal tissue ( P