Cellular signal transduction mechanisms of myocardial ischemia and reperfusion injury
- VernacularTitle:心肌缺血再灌注损伤的细胞信号转导机制
- Author:
Xiao HAN
;
Jianxun LIU
;
- Publication Type:Journal Article
- Keywords:
ischemia;
reperfusion;
cellular signal transduction;
pathogenesis
- From:
Chinese Pharmacological Bulletin
1987;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Cellular signal transduction plays an important role in pathogenesis of myocardial ischemia reperfusion(MIR) injury. During this process, extracellular signal molecules, membrance receptors and intracellular signal paths are involved. There are many cross talkings in signal pathways at many levels. The present article reviews cellular signal transduction mechanisms in MIR. The exploration of MIR's cellular pathogenesis may be beneficial for us to prevent and cure the heart damage in clinic. Furthermore, it may provide a new way of thinking in mechanism research of medicine.