Changes of excitability and contractility in detrusor instability
- VernacularTitle:不稳定膀胱逼尿肌兴奋性及收缩性改变的实验研究
- Author:
Gensheng LU
;
Ci GE
;
Bo SONG
;
Xiyu JIN
;
- Publication Type:Journal Article
- Keywords:
bladder instability;
excitability;
contractility
- From:Journal of Third Military Medical University
2003;0(24):-
- CountryChina
- Language:Chinese
-
Abstract:
Objectives To observe the changes of the detrusor excitability and contractility and to study the mechanism of the unstable bladder. Methods Detrusor strips were obtained from prostectomy patients with benign prostatic hyperplasia. According to the results of urodynamic examination, patients were divided into detrusor instability (DI) and detrusor stability group(DS). Test of mechanical tension and stimulations with electricity and carbachol were performed on the excitability and contractility of the detrusor strips from 8 patients selected from each of the groups in vitro . Results The minimum tension of the detrusor strips when contraction occurred in DI and DS was (0 324?0 132)g and (0 822?0 216)g, respectively. There was significant difference between DI and DS ( P
