Central corneal thickness and corneal endothelium morphology in type 2 diabetes mellitus
- VernacularTitle:2型糖尿病患者角膜厚度和内皮细胞形态学的初步研究
- Author:
Ling YU
;
Hanping XIE
;
Xiaohong MENG
;
Yanji YU
;
- Publication Type:Journal Article
- Keywords:
diabetes mellitus;
cornea;
thickness;
endothelium cell;
morphology
- From:Journal of Third Military Medical University
2003;0(23):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the changes of central corneal thickness(CCT) and corneal endothelium morphology in type 2 diabetes mellitus. Methods The CCT and corneal endothelium morphology in 60 diabetic patients(60 eyes) and 60 healthy volunteers(60 eyes) as the age and gender matched control group were examined by pachymetry and non contact specular microscopy. Stepwise regression analysis was performed to assess the effects of systemic factors on CCT and the corneal endothelial cell density of diabetic patients. Results Compared with that in the control group, the endothelial cell density decreased, and the coefficient of variation of cell area increased significantly( P 0 05). Compared to patients with non proliferative diabetic retinopathy(NPDR), the patients with proliferative diabetic retinopathy(PDR) had a significant reduction in cell density( P
