The progress of study on hyperuricemia
- VernacularTitle:高尿酸血症研究进展
- Author:
Guangliang CHEN
;
Shuyun XU
;
- Publication Type:Journal Article
- Keywords:
hyperuricemia;
gout;
purine;
uric acid
- From:
Chinese Pharmacological Bulletin
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Uric acid is an end product of purine degradation in humans and normally depends upon renal excretion for the majority. Hyperuricemia is likely to cause gout, renal disease, or stones, and associated with cardiovascular impairment over the long term. The prevalence of gout and hyperuricemia appears to be on the increase in recent years. The present paper reviews the relationships between hyperuricemia and insulin resistance,purine metabolism and uric acid elimination , the genetics study and the mechanisms of hyperuricemia.
