Relationship between effects of benazepril and plasma neuropeptide Y in renal hypertensive patients with chronic renal failure
- VernacularTitle:苯那普利对慢性肾衰合并肾性高血压患者的治疗作用与血浆神经肽Y相关性分析
- Author:
Yuwei WANG
;
Daoyou ZHANG
;
- Publication Type:Journal Article
- Keywords:
pharmacodynamics;
benazepril;
chronic renal failure;
renal hypertension;
neuropeptide Y
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2002;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the relationship between the effects of benazepril and plasma neuropeptide Y in renal hypertensive patients with chronic renal failure (CRF). METHODS: The levels of plasma NPY concentration, SBP, DBP and SCr were measured before and after four week treatment with benazepril in thirty renal hypertensive patients. Thirty blood donors from healthy subjects were taken as controls. RESULTS: The plasma NPY concentration was higher in renal hypertensive patients with CRF than in normal controls before and after the treatment. After the treatment, the plasma NPY concentration and SBP, DBP and SCr in renal hypertensive patients were reduced dramatically (P
