Analysis and determination of bacterial resistance of clinical isolates
- VernacularTitle:临床分离菌的耐药性测定与分析
- Author:
Yufu YANG
;
Xiaokun GAO
;
Xianghong HUA
;
- Publication Type:Journal Article
- Keywords:
pharmacodynamics;
clinical isolates;
drug resistance;
antibiotics;
surveillance;
efficacy evaluation
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2002;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To analyze the bacterial resistance of clinical isolates in a hospital. METHODS: Susceptibility of 285 strains of G - bacillus and 133 strains of G + bacillus was observed in 18 kinds of antibiotics. RESULTS: Resistance increased in most G - bacilli to the third generation cephalosporin. The resistance rate was 28.4 % in the 74 strains of staphylococcus aureus, and 3.4 % in enterococci to vancomycin. No vancomycin resistant strain was found. Extend spectrum ? lactamases of E.coli and klebsiella (ESBLs) accounted for 34.0 % and 29.7 %, respectively. CONCLUSION: The drug resistance is severe in antibiotics, indicating that susceptibility determination is important in selection of antibiotics.
