Several problems in studying human embryonic pluripotent stem cells
- VernacularTitle:人胚胎多能干细胞研究中的几个问题
- Author:
Shanrong LIU
;
Zhongtian QI
;
- Publication Type:Journal Article
- Keywords:
embryo;
pluripotent stem cell
- From:
Academic Journal of Second Military Medical University
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Presently, there are 3 problems in the study of human embryonic pluripotent stem cells: short of materials, complicacy of culture system and spontaneous differentiation. Both basic research and clinical application of human embryonic pluripotent stem cells were hindered by these 3 basic problems. New embryonic pluripotent stem cells should be established by combining nucleus transfer and plasma reprograming, and their possible mechanisms and key factors need further study. The culture system should be simplified and cell differentiation must be inhibited when pluripotent stem cell is cultured. When pluripotent stem cells are induced to differentiation, combination of several methods should be used to induce and select specific cell lineages, and the morphology and function of the target cell must be evaluated.