Modulating mechanisms of blood pressure and targets of antihypertensive drugs
- VernacularTitle:血压调控机制与抗高血压药物靶标
- Author:
Xiaofeng YIN
;
Gang HU
;
Hai WANG
;
- Publication Type:Journal Article
- Keywords:
hypertension;
antihypertensive drugs;
target
- From:
Chinese Pharmacological Bulletin
2003;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Hypertension, which has variant of pathogenesis, is one of the most widely spread chronic diseases with serious complications. Antihypertensive drugs can reduce blood pressure and alleviate or reverse cardiovascular remodeling by affecting one or more processes of blood pressure adjusting system. This review focus on targets of antihypertensive drugs associated with Renin angiotensin system, Adrenergic system, Bradykinin Prostacyclin system, Endothelia factor relative system, iron channels and the progresses in the studies of gene therapy for hypertension.