The preventive effects of safflor yellow on myocardium injury of mycardium ischemic reperfusion in rats
- VernacularTitle:红花黄素对大鼠心肌缺血-再灌注模型的作用及机制研究
- Author:
Weichao ZHENG
;
Duobao CHEN
;
Bing LI
;
Lei ZHANG
;
- Publication Type:Journal Article
- Keywords:
safflor yellow;
ischemia reperfusion;
anti lipoperoxidation
- From:
Chinese Pharmacological Bulletin
2003;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM The preventive effects of safflor yefflor (SY) on myocardium injury of myocardium ischemic reperfusion (I/R) was studied. METHODS The contents of MDA activity of SOD,as well as the activity of creatine phospho kinase(CK) and lactate dehydrogenase(LDH) were determined in rat models injured by I/R. RESULTS SY could reduce the activities of CK and LDH ,decrease the the content of MDA in plasmo, and increase the activities of SOD. CONCLUSION SY may obviously prevent the rat I/R model which may be related to its anti lipoperoxidation.
