Progress in molecular biology of pituitary tumor
- VernacularTitle:垂体瘤的分子生物学研究进展
- Author:
Fuquan JIANG
;
Xiaoping ZHOU
;
- Publication Type:Journal Article
- Keywords:
pituitary tumor;
chromosome;
gene
- From:
Academic Journal of Second Military Medical University
2000;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Pituitary tumors, originated from homoral adenohypophyseal cells, are very common in intracranial neoplasms. They are characterized by a wide range of biological behavioral related to hormoral and proliferative activities. Previous pituitary adenoma studies mainly devoted to histological and ultrastructural classification with immunohistochemical techniques. Molecular biology allowed new approaches, especially concerning the pathogenesis and progression. This article reviews the progress of these researches regarding chromosomes, oncogenes, antioncogenes, transgenic animal models and genetic therapy.