Effect of tetrahydrobiopterin on lipid peroxidation in hypercholesterol rabbits
- VernacularTitle:四氢蝶呤对高脂血症兔血清脂质过氧化的影响
- Author:
Jianhui TIAN
;
Chengjun LIU
;
Shan LI
;
- Publication Type:Journal Article
- Keywords:
tetrahydrobiopterin;
hyperlipidemia;
superoxide dismutase;
malondialdehyde;
total cholesterol
- From:
Academic Journal of Second Military Medical University
2000;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
This paper is to observe the effect of tetrahydrobiopterin (BH 4) on lipid peroxidation in hypercholesterol rabbits.A total of 24 rabbits were randomly divided into 4 groups:normal diet(group A),BH 4 plus hypercholesterol diet(group B),VitE plus hypercholesterol diet(group C) and hypercholesterol diet(group D). After 30 d,serum total cholesterol(TC), superoxide dismutase (SOD) and malondialdehyde (MDA) were determined.The amount of TC in group A was lower than that in other groups( P