Effect of allergen at different concentrations on the production of IL-5 by T cells of asthmatic mice
- VernacularTitle:不同浓度过敏原对哮喘小鼠T淋巴细胞产生IL-5的影响
- Author:
Kun SUN
;
Changzheng WANG
;
- Publication Type:Journal Article
- Keywords:
asthma;
T lymphocyte;
apoptosis
- From:Journal of Third Military Medical University
2003;0(16):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of allergen at different concentrations on the production of IL 5 by lymphocytes of mice with asthma and its mechanism. Methods The levels of IL 5 produced by T cells treated with allergen of different concentrations and monocytes as antigen presenting cells in vitro were measured by ELISA and the apoptosis rate of T lymphocytes was determined by TUNEL. Results ① The administration of high dose of allergen inhibited the expression of IL 5( P
