The in vitro antioxidation effect of XMSol on LDL
- VernacularTitle:心脉神口服液抑制低密度脂蛋白体外氧化效应的实验研究
- Author:
Lingyun GAO
;
Zuoyun HE
;
- Publication Type:Journal Article
- Keywords:
Xinmaishen oral liquid;
oxidized LDL;
MDA
- From:Journal of Third Military Medical University
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the in vitro antioxidation effect of Xinmaishen oral liquid(XMSol, a Chinese patent medicine) on low density lipoprotein(LDL). Methods Serum containing XMSol was prepared by serum pharmacological method. The oxidized LDL was obtained by 0.5 mg/ml of LDL in the presence of 10 ?mol/L CuSO 4. XMSol, CuSO 4 and serum containing XMSol and CuSO 4 were added to LDL for incubation. Content of MDA was determined and the antioxidation effect of XMSol was evaluated. Results XMSol could reduce MDA production due to oxidation of LDL in a dose dependent manner. Conclusion XMSol can inhibit the in vitro oxidation of LDL dose dependently.
