Application of phage-displayed peptide libraries
- VernacularTitle:噬菌体肽库展示的应用及其最新进展
- Author:
Hui ZHANG
;
Jinbiao ZHAN
;
Linhai XU
;
Shikun YAN
;
Keyi WANG
;
- Publication Type:Journal Article
- Keywords:
phage display;
peptide libraries;
ligands
- From:
Chinese Pharmacological Bulletin
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Phage display is a new technology developed in recent years. Random peptides displayed on the filamentous phage surface offer a rich source of molecular diversity in searching for ligands that bind an antibody, receptor and other proteins. The phage display system has been effective in the discovery of various ligands. Potential applications of the peptide library include investigation of the protein protein interactions and discovery of mimetic drug candidates.