The experimental animal models of implantation failure
- VernacularTitle:胚泡着床不全的实验动物模型
- Author:
Yunxia WU
;
Guangying HUANG
;
- Publication Type:Journal Article
- Keywords:
animal model;
blastocyst;
ovarum implantation;
implantation rate
- From:
Chinese Pharmacological Bulletin
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM This paper reviews methods of establishing experimental animal models of implantation failure and their observing index METHORDS Pregnant animals were instilled subcutaneously mifepristone, linorpristone, indomethacin,oxytocin or antiserum to ovine FSH, given pregnancy preventing wine to stomach or intrauterine injection of antibody to fibronectin and lamin RESULT The number of imbedded,implantation site and implantation rate of mice was reduced. The number of luteam on ovary was dimimished. Serum progesterone and chorionic gonadotropin levels were significantly decreased CONCLUSION The above methods could establish animal models of implantation failure
