An experimental investigation of the effect of seawater immersion on endothelial cells in dogs sustained by burn-firearm combined injury
- VernacularTitle:弹烧复合伤后海水浸泡对血管内皮细胞影响的实验研究
- Author:
Hong YAN
;
Xinan LAI
;
Hengjiang GE
;
- Publication Type:Journal Article
- Keywords:
burn firearm combined injury;
seawater immersion;
dog;
endothelial cells
- From:Journal of Third Military Medical University
2003;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the influence and mechanism of seawater immersion on endothelial cell injury sustained by burn firearm combined injury to improve the early therapeutic efficacy. Methods The dogs with burn firearm combined injury were randomly divided into two groups: immersion group and control group. In immersion group, the dogs were immersed in seawater for 4 hours, then taken out from seawater. Blood samples were collected from central vein at 4 h, 7 h, 10 h, 20 h and 28 h following wound for the detection of changes of the circulating endothelial cells (CEC) and von Willebrand Factor (vWF). The same procedures except immersion were performed in the control group. Results The levels of CEC and vWF elevated at 4 h and 7 h following wound in control group( P
